SUN2 Rabbit mAb

Catalog Number:

78501

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q9UH99

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human SUN2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF