Cardiac Troponin C Rabbit mAb

Catalog Number:

78489

Amount:

100μg

Price:

$318

Swiss-Prot No:

P63316

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Cardiac Troponin C

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF