TIN2/TINF2 Rabbit mAb

Catalog Number:

78476

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q9BSI4

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human TIN2/TINF2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF