1-832-868-1888
order@swbio.com
Catalog Number: |
78426 |
other_names: | NEFL;CMT1F;CMT2E;NF-L;NF68;NFL;PPP1R110 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P07196 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
Recombinant protein of human Neurofilament L. |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF,IP |
Background: |
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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