RNF20 Rabbit mAb

Catalog Number:

78404

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q5VTR2

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human RNF20

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). [provided by RefSeq, Feb 2012]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF