CD3E+CD3G Rabbit mAb

Catalog Number:

78381

Amount:

100μg

Price:

$318

Swiss-Prot No:

P07766/P09693

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human CD3E+CD3G .

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,ELISA,FC,IF

Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.

References:

appl_detail:

Elisa 1:500 - 1:2000
WB 1:500 - 1:2000
FC 1:50 - 1:200
IF 1:50 - 1:200

Datasheet PDF