MLH1 Rabbit mAb

Catalog Number:

78365

Amount:

100μg

Price:

$318

Swiss-Prot No:

P40692

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human MLH1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF