ANPRB/NRP2 Rabbit mAb

Catalog Number:

78087

Amount:

100μg

Price:

$318

Swiss-Prot No:

P20594

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human ANPRB/NRP2.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF