NME1/NM23A Rabbit mAb

Catalog Number:

78078

Amount:

100μg

Price:

$318

Swiss-Prot No:

P15531

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human NME1/NME1/NM23A

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF