GCLC Rabbit mAb

Catalog Number:

78061

Amount:

100μg

Price:

$318

Swiss-Prot No:

P48506

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human GCLC

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF