FLAP Rabbit mAb

Catalog Number:

78017

Amount:

100μg

Price:

$318

Swiss-Prot No:

P20292

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human FLAP

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF