YB-1/YBX1 Rabbit mAb

Catalog Number:

78011

Amount:

100μg

Price:

$318

Swiss-Prot No:

P67809

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human YB-1/YBX1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF,IP

Background:

This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF