JunB Rabbit mAb

Catalog Number:

77994

Amount:

100μg

Price:

$318

Swiss-Prot No:

P17275

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human JunB

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

JunB is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. AP-1 is a collection of dimers formed by members of the Jun-, Fos-, ATF- and Maf multigene families that bind to specific DNA regulatory elements called AP-1/12-O-tetradecanoylphorbol-13-acetate-responsive elements (TREs) and cAMP-responsive elements (CREs). JunB binds to the DNA sequence 5'-TGA[CG]TCA-3', and involves in the regulation of gene activity following the primary growth factor response. It also acts either as a tumor suppressor or as an oncogene depending on the cell and physiopathological context

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF