NQO1 Rabbit mAb

Catalog Number:

77869

Amount:

100μg

Price:

$318

Swiss-Prot No:

P15559

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human NQO1.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IP

Background:

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF