CD27 Rabbit mAb

Catalog Number:

77861

Amount:

100μg

Price:

$318

Swiss-Prot No:

P26842

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CD27

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF