Bak Rabbit mAb

Catalog Number:

77721

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q16611

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human Bak

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF