Alkaline Phosphatase (ALPL) Rabbit mAb

Catalog Number:

77653

Amount:

100μg

Price:

$318

Swiss-Prot No:

P05186

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Alkaline Phosphatase (ALPL) (ALPL)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF