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CD74 Rabbit mAb

Catalog Number:

77544
other_names: DHLAG, HLADG, II, Ia-GAMMA

Amount:

100μg
calculated_mw: 34kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P04233

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CD74

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

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