Pumilio 1 Rabbit mAb

Catalog Number:

77539

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q14671

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Pumilio 1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF