MMP12 Rabbit mAb

Catalog Number:

77538

Amount:

100μg

Price:

$318

Swiss-Prot No:

P39900

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human MMP12

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF