1-832-868-1888
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Catalog Number: |
77524 |
other_names: | SIR2, SIR2L, SIR2L2 |
Amount: |
100μg |
calculated_mw: | 36kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
Q8IXJ6 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human SIRT2 |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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