L-Plastin/LCP1 Rabbit mAb

Catalog Number:

77412

Amount:

100μg

Price:

$318

Swiss-Prot No:

P13796

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human L-Plastin/LCP1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF