ALAS1 Rabbit mAb

Catalog Number:

77317

Amount:

100μg

Price:

$318

Swiss-Prot No:

P13196

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human ALAS1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF