MRPL28 Rabbit mAb

Catalog Number:

77307

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q13084

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human MRPL28.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF,IP

Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:200

Datasheet PDF