JARID2 Rabbit mAb

Catalog Number:

77296

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q92833

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human JARID2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF