14-3-3 epsilon Rabbit mAb

Catalog Number:

77294

Amount:

100μg

Price:

$318

Swiss-Prot No:

P62258

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human 14-3-3 epsilon

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF