Cofilin Rabbit mAb

Catalog Number:

77282

Amount:

100μg

Price:

$318

Swiss-Prot No:

P23528

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Cofilin.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF