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p73 Rabbit mAb

Catalog Number:

77281
other_names: TP73; P73; tumor protein p73

Amount:

100μg
calculated_mw: 70kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

O15350

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human p73.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

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