PD-1/CD279 Mouse mAb

Catalog Number:

77258

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q15116

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human PD-1/CD279.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF