Integrin alpha 6 (ITGA6/CD49f) Rabbit mAb

Catalog Number:

77253

Amount:

100μg

Price:

$318

Swiss-Prot No:

P23229

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Integrin alpha 6 (ITGA6/CD49f) (ITGA6/CD49f)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF