USP14 Rabbit mAb

Catalog Number:

77226

Amount:

100μg

Price:

$318

Swiss-Prot No:

P54578

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human USP14

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IP

Background:

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:50 - 1:200

Datasheet PDF