Phospho-TBK1/NAK-S172 Rabbit mAb

Catalog Number:

77162

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q9UHD2

Form of Antibody:

Storage/Stability:

Immunogen:

A phospho specific peptide corresponding to residues surrounding S172 of human TBK1/NAK

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. [provided by RefSeq, Oct 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF