TriMethyl-Histone H3-K27 Mouse mAb

Catalog Number:

77087

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q16695

Form of Antibody:

Storage/Stability:

Immunogen:

A synthetic methylated peptide corresponding to residues surrounding K27 of human histone H3

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF,IP,ChIP

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
ChIP 1:20 - 1:100

Datasheet PDF