Glucosylceramidase beta (GBA) Rabbit mAb

Catalog Number:

77086

Amount:

100μg

Price:

$318

Swiss-Prot No:

P04062

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Glucosylceramidase beta (Glucosylceramidase beta (GBA))

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF