Galactosidase alpha (GLA) Rabbit mAb

Catalog Number:

77060

Amount:

100μg

Price:

$318

Swiss-Prot No:

P06280

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Galactosidase alpha (GLA) (GLA)

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF