SUN1 Antibody

Catalog Number:

49956

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O94901

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein corresponding to C-terminal human SUN1.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,ICC,FC

Background:

UNC84A (UNC84 homolog A), also known as SUN1, is a multi-pass nuclear membrane protein that is involved in nuclear anchoring and migration. Highly expressed in heart, brain and testis, UNC84A functions as an A-type Lamin-binding protein that forms a link between the inner and outer nuclear envelope membranes. This link acts as a structural bridge between the nuclear interior and the Actin cytoskeleton and is essential for proper localization of nuclear envelope proteins. Additionally, UNC84A may be involved in telomere attachment and in normal testis development. UNC84A contains one UNC84 (SUN) domain and exists as four isoforms due to alternative splicing events.

References:

appl_detail:

WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:100

Datasheet PDF