DNA Ligase I Antibody

Catalog Number:

49797

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P18858

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB: 1:500
IHC: 1:50-1:200

Datasheet PDF