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Atg16L1 Antibody

Catalog Number:

49751
other_names: A16L1_HUMAN antibody
APG16 like 1 antibody
APG16-like 1 antibody
APG16L antibody
APG16L beta antibody
ATG16 autophagy related 16 like 1 antibody
ATG16 autophagy related 16-like 1 (S. cerevisiae) antibody

Amount:

100μg
calculated_mw: 68/66 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q676U5

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB

Background:

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane. Regulates mitochondrial antiviral signaling (MAVS)-dependent type I interferon (IFN-I) production. Negatively regulates NOD1- and NOD2-driven inflammatory cytokine response. Plays a role in regulating morphology and function of Paneth cell.

References:

appl_detail:

WB: 1:500-1:2,000



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