RANTES Antibody

Catalog Number:	49661
other_names:	Beta chemokine RANTES antibody Beta chemokine RANTES precursor antibody C C motif chemokine 5 antibody CCL 5 antibody CCL5 antibody CCL5_HUMAN antibody Chemokine (C C motif) ligand 5 antibody Chemokine CC M
Amount:	100μg
calculated_mw:	10 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P13501
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB,ICC,IF,IHC
Background:	Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
References:
appl_detail:	WB: 1:500-1:1,000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200
	Datasheet PDF

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