Skp1 Antibody

Catalog Number:	49631
other_names:	Cyclin A/CDK2 associated p19 antibody Cyclin A/CDK2 associated protein p19 antibody Cyclin-A/CDK2-associated protein p19 antibody EMC19 antibody MGC34403 antibody OCP 2 antibody OCP II antibody OCP II protein anti
Amount:	100μg
calculated_mw:	19 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P63208
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC/IF, FC
Background:	Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
References:
appl_detail:	WB: 1:500 ICC: 1:50-1:100 FC: 1:50-1:100
	Datasheet PDF

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