TXNRD1 Antibody

Catalog Number:	49585
other_names:	cytoplasmic antibody Gene associated with retinoic and IFN-induced mortality 12 protein antibody Gene associated with retinoic and interferon-induced mortality 12 protein antibody Gene associated with retinoid IFN induced mortality 12 pr
Amount:	100μg
calculated_mw:	55 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q16881
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC, IHC, IP, FC
Background:	Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx reductases (TrxR1 and TrxR2) are ubiquitous Ly noble flavoproteins that catalyze the NADPH-dependent reduction of Trx as well as several other oxidized cellular components. Mammalian Trx reductases are a part of a selenium-containing pyridine nucleotide-disulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val- Asn-Val-Gly-Cys. TrxR1 and TrxR2 are also involved in the prevention of oxidative stress. Inhibition of TrxR activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.
References:
appl_detail:	WB: 1:500-1:2,000 IHC: 1:50-1:200 ICC: 1:50-1:200 FC: 1:50-1:100
	Datasheet PDF

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