SIRT5 Antibody

Catalog Number:	49271
other_names:	NAD dependent deacetylase sirtuin 5 antibody NAD dependent lysine demalonylase and desuccinylase sirtuin 5 mitochondrial antibody NAD dependent protein deacylase sirtuin 5 mitochondrial antibody NAD-dependent protein deacylase sirtuin-5, mi
Amount:	100μg
calculated_mw:	37/22 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q9NXA8
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB
Background:	SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
References:
appl_detail:	WB: 1:1,000-1:2,000
	Datasheet PDF

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