ATF5 Antibody

Catalog Number:	49148
other_names:	Activating transcription factor 5 alpha/beta antibody Activating transcription factor 5 antibody Activating transcription factor X antibody AFTA antibody ATF 5 antibody ATF 7 antibody ATF7 antibody ATFX antibody BZI
Amount:	100μg
calculated_mw:	31 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:Q9Y2D1
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC/IF, IHC, IP
Background:	Eukaryotic gene transcription is regulated by sequence-specific transcription factors that bind modular cis acting promoter and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The best characterized members of this gene family include CREB-1, CREB-2 (also designated ATF-4), CRE-BPa, LZIP (also designated CREB3 and Luman), CREM-1, CREM-2, ATF-1, ATF-2, ATF-3, ATF-5, ATF-6 and ATF-7. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-5 (ATFx), which can localize to the cytoplasm or the nucleus, binds DNA as a dimer. It interacts with CCND3 and PTP4A1.
References:
appl_detail:	WB: 1:1,000-1:2,000 IHC: 1:50-1:200 ICC: 1:50-1:200
	Datasheet PDF

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