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HNF-4-alpha Antibody

Catalog Number:

49056
other_names: FLJ39654 antibody
FRTS4 antibody
Hepatic nuclear factor 4 alpha antibody
Hepatocyte nuclear factor 4 alpha antibody
Hepatocyte nuclear factor 4 antibody
Hepatocyte nuclear factor 4-alpha antibody
HNF 4 alpha antibody
HNF

Amount:

100μg
calculated_mw: 53 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P41235

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC/IF, IHC, FC

Background:

HNF-4 alpha is a transcription factor that binds DNA as a homodimer. HNF-4 alpha is important in liver, kidney, and intestinal development. It has also been intensely studied as one of a variety of genes responsible for diabetes mellitus. HNF-4 alpha has been shown in knock out mice to be essential for the morphogenic and functional differentiation of hepatocytes. HNF-4 alpha is a dominant regulator of epithelial phenotypes able to drive the mesenchymal-to-epithelial transition when expressed in fibroblasts.

References:

appl_detail:

WB: 1:1,000
IHC: 1:100-1:500
ICC: 1:50-1:200

FC: 1:50-1:100

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