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CD34 Antibody

Catalog Number:

48740
other_names: CD34 antibody
CD34 antigen antibody
CD34 molecule antibody
CD34_HUMAN antibody
Cluster designation 34 antibody
Hematopoietic progenitor cell antigen CD34 antibody
HPCA1 antibody
Mucosialin antibody
OTTHUMP0000003473

Amount:

100μg
calculated_mw: 120 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P28906

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC/IF, IHC, IP

Background:

CD34 is a heavily glycosylated, transmembrane glycoprotein that is expressed on the surface of lymphohematopoietic stem and progenitor cells, small-vessel endothelial cells, embryonic fibroblasts and some cells in fetal and adult nervous tissue. CD34 antigen expression is highest in the most primitive stem cells and is gradually lost as lineage committed progenitors differentiate. The CD34 antigen is also present on capillary endothelial cells and on bone marrow stromal cells. The CD34 cytoplasmic domain has an intracellular domain that contains consensus sites for activated protein kinase C (PKC) phosphorylation as well as serine, threonine and tyrosine phosphorylation consensus sites.

References:

appl_detail:

WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200

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