Topoisomerase II alpha Antibody

Catalog Number:

48581

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P11388

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

peptide

Purification:

Peptide affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC, IHC, FC

Background:

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. It is essential during mitosis and meiosis for proper segregation of daughter chromosomes.

References:

appl_detail:

WB: 1:500
IHC: 1:200
ICC: 1:200

FC: 1:100-1:200

Datasheet PDF