Fibulin 5 Antibody

Catalog Number:

48547

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UBX5

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human Fibulin 5 210-360 aa.

Purification:

Protein affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IHC,FC

Background:

Fibulin proteins contribute to normal development of elastic fiber systems in various types of organs that require elasticity, such as vasculature, lung and skin. Fibulin-5 (EVEC, UP50, DANCE) is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion. Fibulin-5 is also a calcium-dependent elastin-binding protein that scaffolds cells to elastic fibers, thereby preventing elastinopathy in the skin, lung, and vasculature. The Arg-Gly-Asp (RGD) motif in Fibulin-5 interacts with cell surface integrins avb3, avb5 and a9b1, serves as an anchorage for elastic fibers to cells, and promotes organization of elastic fibers. The human Fibulin-5 gene maps to chromosome 14q32.12 and encodes a 488 amino acid protein.

References:

appl_detail:

WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:200

FC: 1:50-1:100

Datasheet PDF