PTBP1 Antibody

Catalog Number:	48201
other_names:	57 kDa RNA binding protein PPTB 1 antibody 57 kDa RNA-binding protein PPTB-1 antibody Heterogeneous nuclear ribonucleoprotein I antibody Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody hnRNP I antibody HNRNP-I antib
Amount:	100μg
calculated_mw:	57 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P26599
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	peptide
Purification:	Peptide affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC, IHC
Background:	Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. It plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. PTBP1 activates exon skipping of its own pre-mRNA during muscle cell differentiation. It binds to the polypyrimidine tract of introns and may promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. PTBP1 may promote the binding of U2 snRNP to pre-mRNA. It cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.
References:
appl_detail:	WB: 1:1000-1:2,000 IHC: 1:200 ICC: 1:200
	Datasheet PDF

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