PI3-kinase p85 subunit alpha Antibody

Catalog Number:	48184
other_names:	GRB1 antibody p85 alpha antibody p85 antibody P85A_HUMAN antibody Phosphatidylinositol 3 kinase associated p 85 alpha antibody Phosphatidylinositol 3 kinase regulatory 1 antibody Phosphatidylinositol 3 kinase, regulatory subu
Amount:	100μg
calculated_mw:	85 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P27986
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	peptide
Purification:	Peptide affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC, IHC, FC
Background:	Phosphatidylinositol 3-kinase regulatory subunit alpha is an enzyme that in humans is encoded by the PIK3R1 gene. Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in three transcript variants encoding different isoforms. Mutations in PIK3R1 are implicated in cases of breast cancer.Mutations in PIK3R1 are associated to SHORT syndrome.
References:
appl_detail:	WB: 1:1,000 ICC: 1:100-1:200
	Datasheet PDF

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