Cytokeratin 7 antibody-Cytoskeleton Marker Antibody

Catalog Number:

48169

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P08729

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to C -terminal cytokeratin 7.

Purification:

Peptide affinity purified.

Specificity/Sensitivity:

Applications:

WB, ICC, IHC, FC

Background:

Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin-7 is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain keratin-7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively.

References:

appl_detail:

WB 1:500
IHC 1:200
ICC 1:200

FC 1:50-1:100

Datasheet PDF